- September 18, 2015 - i3 Pharmaceuticals was formed with strong capital backing from private investors.
- October 1, 2015 – i3 Pharmaceuticals leases laboratory space in Plymouth Meeting, PA.
- January 2, 2016 - i3 Pharmaceuticals acquired a 150,000 square feet building in Warminster, PA.
- December 9, 2016 - i3 Pharmaceuticals moved into the newly constructed facility with state of the art research and analytical laboratories, pilot & commercial manufacturing plants and warehouse.
- June 06, 2018 – i3 Pharmaceuticals filed its first ANDA with the US FDA for a product for which there is presently no generic alternative available.